CASE REPORT
Septic arthritis of the right ankle caused by Staphylococcus aureus infection in a rheumatoid arthritis patient treated with etanercept
Authors
Yuko Waguri-Nagaya1, Masaaki Kobayashi1, Hideyuki Goto1, Shinji Hisazaki1, Atsushi Tsuchiya1 and Takanobu Otsuka1
- Department of Musculoskeletal Medicine, Nagoya City University Graduate School of Medical Sciences, 1 Kawasumi, Mizuho-cho, Mizuho-ku, Nagoya 467-8601, Japan
Received:
27 October 2006
Accepted:
22 March 2007
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Abstract
We report on a 65-year-old man with rheumatoid arthritis who developed septic arthritis of the right ankle and was treated with etanercept, low-dosage prednisolone, and salazosulfapyridine for 18 weeks. Staphylococcus aureus was cultured from ankle synovial fluid; hence, etanercept was stopped and cefazolin was administered. The patient responded well to arthroscopic synovectomy and irrigation of the ankle. Etanercept treatment should cease if it leads to septic arthritis and patients should be prescribed systemic antibiotics, with surgical debridement considered.
Key words
Arthroscopy - Rheumatoid arthritis - Septic arthritis - Staphylococcus aureus - Tumor necrosis alpha antagonist