CASE REPORT

A case of antiphospholipid antibody syndrome that manifested in the course of basal cell carcinoma

Authors

Masanori Funauchi¹, Toshiaki Yamagata¹, Masafumi Sugiyama¹, Shin-ya Ikoma¹, Mika Sakaguchi¹, Koji Kinoshita¹ and Akira Kawata²

1. Department of Nephrology and Rheumatology, Kinki University School of Medicine, 377-2 Ohno-Higashi, Osaka-Sayama 589-8511, Japan
2. Department of Dermatology, Kinki University School of Medicine, Osaka, Japan

Received:

10 October 2006

Accepted:

15 November 2006

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Abstract

A case of antiphospholipid antibody syndrome (APS) is presented, which manifested 5 years after onset of basal cell carcinoma (BCC). There were multiple collateral veins due to portal vein thrombosis. Because immunological abnormalities including anti-cardiolipin β₂ glycoprotein-I antibody improved after surgical resection of BCC, it is likely that APS had occurred as a paraneoplastic syndrome with BCC. This case suggests that it is necessary to investigate the presence of APS when BCC is complicated by some coagulopathies.

Key words

Antiphospholipid antibody syndrome (APS) - Basal cell carcinoma (BCC) - Paraneoplastic - Portal - Thromboembolism