CASE REPORT
Coexistence of nodular regenerative hyperplasia of the liver and pulmonary arterial hypertension in patients with connective tissue diseases: report of three cases and review of the literature
Authors
Hiroyuki Watabe1, Tohru Akahoshi2, Jun Okada2, Shigehiro Kokubu3, Yuko Kurihara4 and Hirobumi Kondo1
| (1) |
Department of Rheumatology and Infectious Diseases, Kitasato University School of Medicine, 1-15-1 Kitasato, Sagamihara, Kanagawa 228-8555, Japan |
| (2) |
Department of General Medicine, Kitasato University School of Medicine, Kanagawa, Japan |
| (3) |
Department of Gastroenterology, Kitasato University School of Medicine, Kanagawa, Japan |
| (4) |
Department of Internal Medicine, Kawasaki Ida Municipal Hospital, Kanagawa, Japan |
Full Text（PDF)
Received: December 22, 2005 Accepted: July 18, 2006
Abstract
Nodular regenerative hyperplasia of the liver
(NRH) is known to be a rare condition in patients with
connective tissue diseases (CTD). In this report, we document
three patients with CTD who had both NRH and
pulmonary hypertension (PH). All three patients developed
PH during their course and thereafter developed
NRH. The clinical course of these patients suggests that
circulatory disturbance caused by PH might be a trigger for
NRH.
Key words
Connective tissue diseases (CTD), Nodular regenerative hyperplasia of the liver (NRH), Pulmonary hypertension
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