CASE REPORT
A case of severe acute pancreatitis, in overlap syndrome of systemic sclerosis and systemic lupus erythematosus, successfully treated with plasmapheresis
Yukie Suzuki1, Hiroshi Okamoto1, Kyoko Koizumi1, Mutsuto Tateishi1, 2, Masako Hara1 and Naoyuki Kamatani1
| (1) |
Institute of Rheumatology, Tokyo Women's Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054, Japan |
| (2) |
Department of Rheumatology, Tokyo Metropolitan Ohtsuka Hospital, Tokyo, Japan |
Received: 13 February 2006 Accepted: 24 March 2006
Abstract Here, we describe a case of severe pancreatitis in overlap syndrome of systemic lupus erythematosus (SLE) and systemic sclerosis (SSc) in an adult female patient. Treatment with plasmapheresis and high-dose prednisone successfully saved her life and led to remission of the pancreatitis. This is the first case report of severe acute pancreatitis in the setting of overlap syndrome of SLE and SSc. The advantages and disadvantages of the use of corticosteroids are discussed.
Key words Corticosteroid - Overlap syndrome - Plasmapheresis - Severe acute pancreatitis - Systemic lupus erythematosus (SLE) - Systemic sclerosis (SSc) - T helper type 1 cell
