CASE REPORT
Rheumatoid arthritis-associated corneal ulceration complicated by bacterial infection
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Takeshi Ide1, Hiroyuki Matsuda2, Kohji Nishida1, Naoyuki Maeda1, Hitoshi Watanabe3 and Yoshitsugu Inoue4
| (1) |
Department of Ophthalmology, Osaka University Medical School, Suita, Japan |
| (2) |
Department of Ophthalmology, Kenporen Osaka Central Hospital, Osaka, Japan |
| (3) |
Department of Ophthalmology, Kansai Rosai Hospital, Amagasaki, Japan |
| (4) |
Division of Ophthalmology and Visual Science, Faculty of Medicine, Tottori University, 36-1 Nishimachi, Yonago 683-8504, Japan |
Received: 10 August 2005 Accepted: 17 October 2005
Abstract We report two cases of rheumatoid ocular disease complicated by infection of methicillin-sensitive Staphylococcus aureus (MSSA) in one case, and methicillin-resistant Staphylococcus aureus (MRSA) in the other. In both cases, punctal occlusion and immunosuppressive therapy were presumed to be major risk factors of the infections. In addition, the characteristic feature was corneal melting, which is probably accelerated by infection. To avoid infectious progression and melting, potent antibiotics followed by immunosuppressive therapy were necessary.
Key words Corneal melting - Immunosuppression - Infection - Methicillin-resistant Staphylococcus aureus (MRSA) - Rheumatoid arthritis (RA)
