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MODERN RHEUMATOLOGY Vol.15 No.5

Vol.15 No.5 に戻る

CASE REPORT

Massive mesenteric edema in a patient with type I hereditary angioedema

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Yoshiki Sekijima1 , Takao Hashimoto1, Hiroshi Koshihara1, Yasuhiro Kawachi2, Fujio Otsuka2 and Shu-ichi Ikeda1

(1) Third Department of Medicine, Shinshu University School of Medicine, 3-1-1 Asahi, Matsumoto 390-8621, Japan
(2) Department of Dermatology, Institute of Clinical Medicine, University of Tsukuba, Tsukuba, Japan

Received: 30 November 2004 Accepted: 31 May 2005

Abstract We report a patient with hereditary angioedema (HAE) presenting with skin edema and abdominal pain. Laboratory examination showed reduced levels of CH50, C2, C4, and C1 inhibitor (C1-INH). Abdominal computed tomography (CT) showed marked mesenteric edema and wall thickening of the duodenum and transverse colon. Acute abdominal pain is common in HAE and is difficult to distinguish from surgical emergency. Massive mesenteric edema on CT is a rare, but specific, sign suggesting HAE.

Key words Abdominal pain - C1 inhibitor (C1-INH) - Computed tomography (CT) - Hereditary angioedema (HAE) - Mesenteric edema

 

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