CASE REPORT
Progressive facial hemiatrophy complicated by sclerodactyly, Raynaud’s phenomenon, anti-ribonucleoprotein antibody, and trigeminal nerve disturbance
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Ken Hamasaki1 , Kanae Kubo1, 2 and Hiroko Kanda2
| (1) |
Department of Rheumatology, Tokyo Metropolitan Geriatric Hospital, 35-2 Sakae-cho, Itabashi-ku, Tokyo 173-0015, Japan |
| (2) |
Department of Allergy and Rheumatology, Faculty of Medicine, University of Tokyo, Tokyo, Japan |
Abstract A Japanese woman was diagnosed as having progressive facial hemiatrophy when she was 26 years old. After 30 years, Raynaud’s phenomenon and sclerodactyly suddenly appeared; at the same time, positive rheumatoid factor and anti-ribonucleoprotein (anti-RNP) antibody were noted on serological examinations. When she was 60 years old, trigeminal nerve disturbance also appeared. The associations between progressive facial hemiatrophy, systemic scleroderma, and trigeminal nerve disturbance are interesting and should be discussed.
Key words Anti-ribonucleoprotein (anti-RNP) antibody - Progressive facial hemiatrophy - Raynaud’s phenomenon - Sclerodactyly - Trigeminal nerve disturbance |