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CASE REPORT
Sensorimotor polyneuropathy as an initial clinical manifestation of sarcoidosis

Shinji Sato1 , Shigeru Nogawa1, Michito Hirakata1, Hideko Iizuka1, Akira Suwa1, Tsuneyo Mimori2 and Yasuo Ikeda1

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(1) Department of Internal Medicine, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, Tokyo 160-8582, Japan
(2) Department of Rheumatology and Clinical Immunology, Kyoto University Graduate School of Medicine, Kyoto, Japan

Received: 11 August 2004 Accepted: 12 January 2005

Abstract A 45 year-old Japanese woman developed numbness and tingling of both hands and feet. Electrophysiological examination revealed sensorimotor polyneuropathy. She was diagnosed as suffering from sarcoidosis on the basis of the pathological findings from dermal biopsy. Steroid therapy effectively improved the clinical symptoms. Although sarcoid neuropathy is rare, this case suggests sensorimotor polyneuropathy is an important symptom of sarcoidosis and can represent the initial clinical manifestation of the disease.

Key words Axonal degeneration - Electromyography (EMG) - Sarcoidosis - Sensorimotor polyneuropathy


 

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