MR Vol.14 No.6 indexに戻る


MODERN RHEUMATOLOGY Vol.14 No.6             
Gustatory sweating due to autonomic neuropathy in a patient with amyloidosis secondary to rheumatoid arthritis
Tadashi Nakamura1, Kunihiko Tomoda2, Michishi Tsukano2, Yuji Yamamura1 and Satoshi Baba3
(1) Internal Medicine and Rheumatology Section, Kumamoto Center for Arthritis and Rheumatology, 1-15-7 Kuhonji, Kumamoto 862-0976, Japan
(2) Orthopaedics and Rheumatology Section, Kumamoto Center for Arthritis and Rheumatology, Kumamoto, Japan
(3) Clinical Pathology Section, Fukuroi Municipal Hospital, Shizuoka, Japan
Abstract
Autonomic neuropathy, although often reported to occur in patients with AL (amyloid of light chain of immunoglobulin) amyloidosis, is extremely rare in AA (amyloid A) amyloidosis. We describe a patient with AA amyloidosis secondary to rheumatoid arthritis (RA) in whom autonomic neuropathy resulted in gustatory sweating during the end stage of RA. We discuss the importance of gustatory sweating as a characteristic sign of autonomic nervous system dysfunction in AA amyloidosis secondary to RA, and stress the availability of cardiovascular autonomic tests as an indicator of autonomic neuropathy in not only AL amyloidosis but also AA amyloidosis.
 
Key words
Amyloidosis - Dysautonomia - Gustatory sweating - Rheumatoid arthritis (RA)
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