MR Vol.14 No.5 indexに戻る

MODERN RHEUMATOLOGY Vol.14 No.5             
A case with chronic fatigue syndrome with positive antinuclear antibody followed by postpartum thyroiditis
Yasuhiko Itoh1, Hisamitsu Hamada1, Tohru Igarashi1, Natsuko Kuwabara1, Taiyo Imai1, Osamu Fujino1 and Yoshitaka Fukunaga1

(1) Department of Pediatrics, Nippon Medical School, 1-1-5 Sendagi, Bunkyo-ku, Tokyo 113-8603, Japan

Received: 10 January 2004 Accepted: 01 June 2004
Abstract
Autoimmune fatigue syndrome (AIFS) is defined by chronic nonspecific complaints, a positive antinuclear antibody (ANA) assay, and the absence of another explanation for the complaints. Some severe cases fulfill the criteria for chronic fatigue syndrome (CFS). CFS is a syndrome characterized by disabling severe fatigue and defined by the criteria proposed by the U.S. Centers for Disease Control and Prevention. In this report, a patient with chronic fatigue syndrome and positive ANA assay was described as having developed postpartum thyroiditis 5 years after the onset. Subchemical hypothyroidism is characterized by clinical hypothyroidism not meeting biochemical criteria but showing evidence of thyroid autoimmunity. The relation between AIFS and subchemical hypothyroidism is discussed.
 
Key words
Antinuclear antibodies (ANAs) - Anti-thyroid anti-bodies - Autoimmune fatigue syndrome (AIFS) - Chronic fatigue syndrome (CFS) - Hypothyroidism
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