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MR Vol.14 No.2 indexに戻る
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MODERN RHEUMATOLOGY
Vol.14 No.2 |
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MPO-ANCA-positive Wegeners granulomatosis presenting
with hypertrophic cranial pachymeningitis: case report and review
of the literature
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| Mitsuteru Akahoshi1, Goichi Yoshimoto1, Hitoshi
Nakashima1 , Katsuhisa Miyake1, Yasushi Inoue1, Yosuke Tanaka1, Hiroshi
Tsukamoto1, Takahiko Horiuchi1, Takeshi Otsuka1 and Mine Harada1 |
| (1) Department of Medicine and Biosystemic
Science, Graduate School of Medical Sciences, Kyushu University,
3-1-1 Maidashi, Higashi-ku, Fukuoka, 812-8582, Japan |
Received: 15 July 2003 Accepted: 13 January
2004 |
| Abstract |
We describe a case of hypertrophic cranial
pachymeningitis (HCP) associated with Wegeners granulomatosis (WG)
in a 60-year-old
man presenting with chronic headache and multiple cranial nerve neuropathies.
A test for antibodies to the neutrophil cytoplasmic protein myeloperoxidase
(MPO-ANCA) was positive in this case. We review the literature on
perinuclear (p)-ANCA-related HCP, including our case. This case indicates
the link between MPO-ANCA-positive WG and HCP.
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| Key words |
| Hypertrophic cranial pachymeningitis
(HCP) - MPO-ANCAWegeners granulomatosis (WG) |
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