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MR Vol.14 No.1 indexに戻る
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MODERN RHEUMATOLOGY
Vol.14 No.1 |
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Hemagglutination of preoperative blood donation
in patients with rheumatoid arthritis |
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| Seiji Tsuboi1 , Yukihisa Tamura1, Takayoshi Fujibayashi1,
Seiki Iwasada1 and Nobumasa Miyake2 |
(1) Deparment of Rheumatology, Shizuoka Kousei
Hospital, 23 Kitabanncho, Shizuoka, 420-8623, Japan
(2) Miyake Clinic of Orthopedic Surgery, Shizuoka, Japan |
Received: 28 January 2003 Accepted: 24 June 2003 |
| Abstract |
| Abstract We gave preoperative blood transfusions
to 37 patients with rheumatoid arthritis (RA) and 35 patients with
osteoarthritis (OA), including some whose baseline hemoglobin level
was less than 10g/dl. Transfusion packs can preserve whole blood
containing citrate phosphate dextrose (CPD) for 3 weeks. The baseline
hemoglobin level of RA cases was 10.4g/dl (range 8.4?13.1g/dl), and
that of OA cases was 11.9g/dl (range 10.4?15.0g/dl). By collecting
200?400g every week before the operation, the total was 800?1200g.
Erythropoietin was given to patients intramuscularly when their hemoglobin
was less than 13g/dl after blood had been collected. Hemagglutination,
with diameters of more than 1cm, made filter occlusions in 11 RA
cases (30%) and one OA case (3%) (P 0.0031) after retransfusion.
There were no differences between hemagglutination patients (agglutination
group) and nonhemagglutination patients (nonagglutination group)
regarding baseline C-reactive protein (CRP), white blood cells, platelets,
or fibrinogen. We could not predict the formation of macrohemagglutination
in the packs collected during the clinical course. In RA cases, allogenic
transfusions were performed for four cases (36%) in the agglutination
group and for one case (12%) in the nonagglutination group. Preoperative
transfusion for the RA patients showed hemagglutination in some cases,
and highlighted the need for modifications to reduce these hemagglutinations. |
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| Key words |
| Key words Agglutination - Blood donation - Rheumatoid
arthritis (RA) |
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