 |
MR Vol.13 No.4 indexに戻る
 |
MODERN RHEUMATOLOGY
Vol.13 No.4 |
 |
|
|
 |
|
|
A case of pachydermoperiostosis associated with
arthritis
|
|
|
| Tomoko Matsumoto1 , Toshiyuki Tsurumoto1 and
Hiroyuki Shindo1 |
| (1) Department of Orthopedic Surgery, School
of Medicine, Nagasaki University, 1-7-1 Sakamoto, Nagasaki, 852-8501,
Japan |
| |
| Received: 08 February 2003 Accepted: 11 June
2003 |
| |
| Abstract |
| Pachydermoperiostosis (PDP) is characterized
by clubbing fingers, furrowing of the facial skin, and perio-steal
hypertrophy. We report a case of a patient with PDP associated with
severe arthritis of the knee and ankle joints. His serum C-reactive
protein (CRP) levels were increased, and an analysis of serum and
synovial fluid showed high levels of interleukin-6. These findings
mean that there is some difficulty in distinguishing the disease
from rheumatoid arthritis. While treatments such as nonsteroidal
anti-inflammatory drugs, steroids, and colchicine were not particularly
effective, the severe arthralgia was gradually relieved over a few
years. |
| |
| Key words |
| Arthritis - Clubbing fingers - Pachydermoperiostosis
(PDP) |
|
|
 |
|
|
