MR Vol.13 No.3 indexに戻る

MODERN RHEUMATOLOGY Vol.13 No.3             
A case of ochronotic arthropathy treated with total hip arthroplasty
Shinichi Inoue1, Yasuo Iwata1 , Kousei Yoh1, Yoshiteru Nakamura1 and Souji Maruo1
(1) Department of Orthopedic Surgery, Hyogo College of Medicine, 1-1 Mukogawa-cho, Nishinomiya, 663-8501, Japan
 
Received: 31 July 2002 Accepted: 20 December 2002
 
Abstract
We report a case of ochronotic arthropathy treated with total hip arthroplasty. The articular cartilage of the patient''s femoral head and synovium displayed black pigmentation. Microscopically, the articular cartilage revealed reddish-brown pigmentation (particularly in deep cartilage), necrotic chondrocytes, and slight black pigmentation in the cytoplasm of chondrocytes. Electron microscopy revealed electron-dense material deposited predominantly along and between collagen fibers.
 
Key words
Alcaptonuria - Ochronotic arthropathy - Total hip arthroplasty
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