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MR Vol.13 No.3 indexに戻る
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MODERN RHEUMATOLOGY
Vol.13 No.3 |
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Assessment of inflamed synovial membrane in the
knee joint by dynamic magnetic resonance imaging |
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| Mitsumasa Kawai1, Akito Nishimura2, Toshiaki
Ikeda1, Hirahito Endo3, Miyoko Rana3, Moritoshi Itoman4 and Kiyoko
Sakurai1 |
(1) Kitasato University Graduate School of Medical
Science, 1-15-1 Kitasato, Sagamihara, 228-8555, Japan
(2) Division of Orthopedic Surgery, Nakaizu Spa Hospital, Tagata-gun, Shizuoka,
Japan
(3) Department of Internal Medicine, School of Medicine, Kitasato University,
Sagamihara, Japan
(4) Department of Orthopedic Surgery, School of Medicine, Kitasato University,
Sagamihara, Japan
(5) Present address: 6-3-3-1308 Fujimi, Sagamihara, 229-0036, Japan |
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| Received: 01 October 2002 Accepted: 19 December
2002 |
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| Abstract |
| Dynamic magnetic resonance imaging (dynamic MRI)
was used to examine the synovial membrane in the knee joints of 15
patients with rheumatoid arthritis (RA) in order to investigate the
relationship between pathological and MRI findings. Signal intensities
in the regions of interest (ROI), identified as the synovial membrane
of the suprapatellar pouch, were measured on MR images. Signal intensities
at various times after the injection of contrast medium Gd?diethylenetriaminopentoacetic
acid (Gd?DTPA) were normalized relative to the signal intensity at
80s, and designated as the normalized signal intensity (NSI). Pathological
findings were quantified, and the types of inflamed synovial membrane
were classified as either acute or chronic. A significant difference
in NSI was observed between acute and chronic types (P 0.05). Dynamic
MRI was capable of classifying acute and chronic RA by measuring
NSI 20s after contrast medium injection. Dynamic MRI was therefore
shown to be useful for assessing regional synovial inflammation. |
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| Key words |
| Dynamic magnetic resonance imaging (Dynamic MRI)
- Gd-diethylenetriaminopentoacetic acid (Gd?DTPA) - Normalized
signal intensity (NSI) - Rheumatoid arthritis (RA) - Suprapatellar
pouch |
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