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MR Vol.13 No.1 indexに戻る
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MODERN RHEUMATOLOGY
Vol.13 No.1 |
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Ochronotic spondylarthropathy: two case reports
of progressive destructive changes in the hip |
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| M. Takagi1, H. Ida1, S. Kobayashi1, M.
Ishii2, T. Osanai1, Y. T. Konttinen3 |
(1)Department of Orthopaedic Surgery, Yamagata
University School of Medicine, 2-2-2 Iida-Nishi, Yamagata 990-9585,
Japan
(2)Department of Orthopaedic Surgery, Saiseikai Yamagata Hospital, Yamagata,
Japan
(3)Orton Research Institute, Orthopaedic Hospital of the Invalid Foundation,
Helsinki Invartes Medicin, and Department of Internal Medicine, Helsinki University
Central Hospital, Finland |
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| Abstract |
| Abstract We report two cases of ochronotic
spondylarthropathy who presented with spinal involvement followed
by progressive destructive changes in the hip joint, which led
to total hip replacement with a satisfactory outcome. Pathological
examination revealed severe deterioration of the affected hip with
unique cartilage degeneration associated with active inflammation
in the synovium and bone marrow. These features were also evaluated
by magnetic resonance imaging in one case which presented with
rapidly destructive changes in the hip. Spinal involvement may
contribute to progressive destructive hip arthropathy in ochronosis. |
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| Key words |
| Key words Alkaptonuria (AKU) ・ Ochronosis
・ Rapidly destructive hip joint ・ Spondylarthropathy |
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