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MR Vol.12 No.4 indexに戻る
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MODERN RHEUMATOLOGY
Vol.12 No.4 |
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Association of subacute cutaneous lupus
erythematosus in a rheumatoid arthritis patient with Sjogren's
syndrome |
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| K. Migita2, M. Udono2, H. Kimura1, K. Eguchi3 |
(1)Department of Internal Medicine, National
Nagasaki Medical Center, Omura, Japan
(2)Department of Dermatology, National Nagasaki Medical Center, Omura, Japan
(3)First Department of Internal Medicine, Nagasaki University School of Medicine,
1-7-1 Sakamoto, Nagasaki 852-8501, Japan |
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| Abstract |
| Abstract In this paper, we report a case of rheumatoid
arthritis (RA) with Sjogren's syndrome (SS) in which the patient
developed subacute cutaneous lupus erythematosus (SCLE). A 72-year-old
woman, who had a 10-year history of RA and SS, developed annular
erythematosus skin lesions involving her face, neck, and extremities.
Serological tests showed that anti-SS-A/Ro antibodies and anti-DNA
antibodies were elevated. Histological examination of the skin lesions
demonstrated the liquefaction degeneration of the epidermal basal
layer and perivascular mononuclear cell infiltration. The diagnosis
of SCLE was made based on the clinical features and skin histological
findings. The disease was well controlled with intralesional and
systemic corticosteroids and became quiescent. This case report demonstrates
the concurrence of sero-positive RA, SS, and SCLE, which seems to
be quite rare. |
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| Key words |
| Key words Anti-SS-A/Ro antibody ・ Rheumatoid
arthritis (RA) ・ Sjogren's syndrome (SS) ・ Subacute cutaneous
lupus erythematosus (SCLE) |
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