MR Vol.12 No.4 indexに戻る

MODERN RHEUMATOLOGY Vol.12 No.4             
Cyclosporin-A ameliorated interstitial pneumonitis in a patient with amyopathic dermatomyositis
M. Aoki1, Y. Matsukawa1, M. Kaneko1, T. Hattori1, T. Shimizu1, S. Nishinarita1, T. Horie1
(1)First Department of Internal Medicine, Nihon University School of Medicine, Oyaguchi-Kamimachi, Itabashi-ku, Tokyo 173-8610, Japan
 
Abstract
Abstract A 40-year-old woman with amyopathic dermatomyositis (ADM) developed acute pneumonitis. Despite pulse methylprednisolone therapy, the pneumonitis worsened. We therefore initiated cyclosporin-A (Cy-A) therapy with success, although Pneumocystis carinii (PC) pneumonia occurred. Coexistence of dermatomyositis (DM)-related pneumonitis and PC pneumonia was diagnosed by means of chest X-ray findings, KL-6, and polymerase chain reaction (PCR) for PC. We thus continued Cy-A therapy to ameliorate the pneumonitis. Cy-A appeared to be effective for corticosteroid-resistant pneumonitis in a patient with DM.
 
Key words
Key words Cyclosporin-A (Cy-A) ・ Dermatomyositis (DM) ・ Interstitial pneumonitis (IP) ・ KL-6 ・ Pneumocystis carinii (PC)
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