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MR Vol.12 No.2 indexに戻る
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MODERN RHEUMATOLOGY
Vol.12 No.2 |
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Severe hypertension associated with multiple
intrarenal microaneurysms in a patient with systemic lupus erythematosus
and antiphospholipid antibodies |
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| A. Furuta1, T. Fujii2, H. Yasuoka1, R.
Takada1, M. Hirakata1, T. Mimori2 |
(1)Department of Internal Medicine, Keio University
School of Medicine, Tokyo, Japan
(2)Department of Rheumatology and Clinical Immunology, Kyoto University
Graduate School of Medicine, 54 Shogoin-Kawahara-cho, Sakyo-ku,
Kyoto 606-8507, Japan |
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| Abstract |
Abstract A 26-year-old Japanese woman with
systemic lupus erythematosus (SLE) developed severe hyperten-sion
and an increased active renin concentration (ARC), ischemic colitis,
and splenic infarction. She had antiphospholipid antibodies (APA),
multiple intrarenal microaneurysms, and multiple stenoses of the
mesenteric arteries. Combination therapy with antihypertensive
agents, aspirin, warfarin, and corticosteroids (30 mg daily) controlled
her abdominal symptoms and hypertension. Multiple intrarenal microaneurysms
in SLE with APA may be the cause of severe hypertension and elevated
serum ARC.
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| Key words |
Key words Active renin concentration (ARC) ・ Antiphospholipid
antibodies (APA) ・ Hypertension ・ Microaneurysm ・ Systemic lupus
erythematosus (SLE)
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