MR Vol.12 No.1 indexに戻る

MODERN RHEUMATOLOGY Vol.12 No.1             
A case of eosinophilic myositis associated with orbital myositis
M. Nakashima1, Y. Kawabe1, T. Aoyagi1, I. Furuichi1, K. Maeda1, S. Naito2, A. Kawakami3, K. Eguchi3
(1)Department of Rheumatology, National Ureshino Hospital, 2436 Shimojuku Hei, Ureshino-machi, Fujitsu-gun, Saga 843-0393, Japan
(2)Department of Pathology, National Ureshino Hospital, Fujitsu-gun, Saga, Japan
(3)1st Department of Internal Medicine, School of Medicine, Nagasaki University, Nagasaki, Japan
 
Abstract
Abstract A 29-year-old woman was admitted to our hospital because of fever, myalgia, and ocular pain. She had been given norgesterone and ethinylestradiol orally. Laboratory data indicated the presence of systemic inflammation together with elevated levels of muscle enzymes. Magnetic resonance imaging revealed inflammatory lesions in skeletal and extraocular muscles. The diagnosis of eosinophilic myositis was based on histopathological examination of the deltoid muscle, which showed infiltration of eosinophils into the tissue with necrotizing muscle fibers. Prednisolone treatment resulted in marked clinical improvement. This is the first case report of eosinophilic myositis in which the extraocular muscles were affected.
 
Key words
Key words Eosinophilic myositis ・ Estradiol ・ Orbital myositis
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