MR Vol.11 No.4 indexに戻る

MODERN RHEUMATOLOGY Vol.11 No.4             
Primary Sjogren's syndrome complicated by sarcoidosis and psoriasis vulgaris
K. Hirayama1, S. Shiokawa1, Y. Miyazaki1, M. Nakamura1, S. Motomura1, Y. Suehiro1, Y. Yoshikawa2, S. Ikuyama1, J. Nishimura1
(1)Department of Clinical Immunology, Medical Institute of Bioregulation, Kyushu University, 4546 Tsurumihara, Beppu 874-0838, Japan Tel. +81-977-27-1640; Fax +81-977-27-1641 e-mail: sahasu@tsurumi.beppu.kyushu-u.ac.jp
(2)Department of Pathology, Medical Institute of Bioregulation, Kyushu University, Beppu, Japan
 
Abstract
Abstract Primary Sjogren's syndrome (SS), sarcoidosis (SA), and psoriasis vulgaris (PV) are all chronic diseases of unknown etiology. Recent studies suggest that activated T cells play a central role in their pathogenesis. We describe a case of a Japanese woman with primary SS complicated by SA and PV. To our knowledge, this is the first case in which these three diseases coexist. Although these three disorders may have a common immunopathogenic mechanism, the extreme rarity of their coexistence suggests that distinct etiological mechanisms are also involved and appear to play an important role in triggering and developing each disease.
 
Key words
Key words Psoriasis ・ Sarcoidosis (SA) ・ Sjogren's syndrome (SS) ・ T lymphocytes
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