MR Vol.11 No.4 indexに戻る

MODERN RHEUMATOLOGY Vol.11 No.4             
Two cases of reactive hemophagocytic syndrome: a patient with adult-onset Still's disease and a patient with herpes zoster and autoimmune abnormalities
J. Susuki1, M. Nawata1, M. Koike1, R. Wada2, I. Sekigawa1, N. Iida1, H. Hashimoto3
(1)Department of Medicine, Juntendo University Izu-Nagaoka Hospital, 1129 Nagaoka, Izu-Nagaoka-cho, Tagata-gun, Shizuoka 410-2295, Japan
(2)Department of Pathology, Juntendo University Izu-Nagaoka Hospital, Tagara-gun, Shizuoka, Japan
(3)Department of Internal Medicine and Rheumatology, Juntendo University School of Medicine, Tokyo, Japan
 
Abstract
Abstract We report two cases of bone marrow hemophagocytosis. One patient had adult-onset Still's disease, and the other had herpes zoster associated with potential autoimmune abnormalities. Our findings suggested a pos-sible role of cytokines and/or antibodies in the induction of hemophagocytosis in patients with connective tissue diseases and/or immune abnormalities.
 
Key words
Key words Adult-onset Still's disease (AOSD) ・ Reactive hemophagocytic syndrome (HPS) ・ Virus-associated hemophagocytic syndrome (VAHS)
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