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MR Vol.11 No.4 indexに戻る
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MODERN RHEUMATOLOGY
Vol.11 No.4 |
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Diagnosis and therapy of rheumatoid arthritis
in the future |
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| N. Matsui1, Y. Waguri-Nagaya1, Y. Taneda1 |
| (1) Department of Orthopedic Surgery, Nagoya
City University, Medical School, 1 Kawasumi, Mizuho-cho, Mizuho-ku,
Nagoya 467-8601, Japan |
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| Abstract |
| Abstract Rheumatoid arthritis (RA) is a chronic,
inflammatory, systemic disease characterized by joint pain and
destruction. We describe the importance of early diagnosis, recording
magnetic resonance images images at an early stage, monitoring
disease progression using gliostatin purified in our laboratory,
and sugar-chain analysis of RA serum IgG. For treatment of RA,
cyclooxygenase-2-selective inhibitors, disease-modifying antirheumatic
drugs, biological products, and the possibility of gene therapy
are discussed. The development of therapeutic methods based on
the elucidation of the pathology of RA has progressed markedly
in the past decade, and further progress and the development of
an early diagnostic method are expected. |
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| Key words |
| Key words Agalactosyl IgG ・ Cyclooxygenase
(COX)-2 selective inhibitor ・ Gliostatin ・ Magnetic resonance imaging
(MRI) ・ Rheumatoid arthritis |
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