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MR Vol.11 No3 indexに戻る
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MODERN RHEUMATOLOGY
Vol.11 No.3 |
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Immune thrombocytopenic purpura associated with
rheumatoid arthritis - a report of five cases and review of the literature |
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| N. Ichikawa1, M. Harigai1, A. Nakajima1,
M. Hara1, N. Kamatani1 |
| (1)Institute of Rheumatology, Tokyo Women's
Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo 162-0054,
Japan |
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| Abstract |
| Abstract Immune thrombocytopenic purpura (ITP)
associated with rheumatoid arthritis (RA) is relatively rare. We
describe five cases of RA with ITP. In all five patients, platelet
counts were low, platelet-associated IgG levels were elevated,
and bone marrow aspiration showed megakaryocytosis. Glucocorticoid
therapy was effective in three cases, but the other two cases required
immunosuppressants or intravenous %-globulin in addition to glucocorticoid.
We review the reported cases of RA with ITP and discuss the pathophysiology
and differential diagnosis of thrombocytopenia in RA. |
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| Key words |
| Key words Felty's syndrome ・ Immune thrombocytopenic
purpura ・ Rheumatoid arthritis ・ Rhupus syndrome |
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