 |
MR Vol.11 No.2 indexに戻る
 |
MODERN RHEUMATOLOGY
Vol.11 No.2 |
 |
|
|
 |
|
|
Systemic sclerosis in two second cousins: a case
report |
|
|
| T. Kuroda1, S. Murakami2, S. Honda1, Y.
Ohfuchi2, S. Hirose1, H. Hasegawa1, A. Murasawa2, M. Nakano1, F.
Gejyo1 |
(1)Department of Medicine II, Niigata University
School of Medicine, 1-757 Asahimachi-dori, Niigata 951-8510, Japan
(2)Department of Rheumatology, Niigata Prefectural Senami Hospital, Murakami,
Niigata, Japan |
| |
| Abstract |
| Abstract We describe two second cousins who developed
systemic sclerosis. These patients had major histocompatibility complex
(MHC) class I alleles in common, including A2, A26(10), B60(40),
and Cw7 as well as class II allele DR2. This DR2 was thought to be
associated with the onset of the disease. Our patients both experienced
a limited type of systemic sclerosis, but the expression of autoantibodies
was different. |
| |
| Key words |
| Key words HLA ・ Relatives ・ Systemic sclerosis |
|
|
 |
|
|
