MR Vol.11 No.1 indexに戻る

MODERN RHEUMATOLOGY Vol.11 No.1             
Dextromethorphan for neuropathic pain with Churg-Strauss syndrome
M. Harada1, R. Kuwahara1, H. Yoshida1, O. Hashimoto1, M. Sakamoto1, Y. Koga1, T. Kano2, M. Sata1
(1)Second Department of Medicine, Kurume University School of Medicine, 67 Asahi-machi, Kurume 830-0011, Japan Tel. +81-942-31-7561; Fax +81-942-34-2623 e-mail: harada@med.kurume-u.ac.jp
(2)Anesthesiology, Kurume University School of Medicine, Kurume, Japan
 
Abstract
Abstract A 48-year old man who had been treated with prednisolone, aminophylline, and pranlukast, a leukotriene-receptor antagonist, was diagnosed with Churg-Strauss syndrome based on the findings of asthma, eosinophilia, mononeuropathy, and extravascular eosinophils. Intractable neuropathic pain of the legs was successfully controlled with an N-methyl-d-aspartate receptor antagonist, dextromethorphan. We suggest that dextromethorphan receptor antagonists may be a useful treatment for the pain of neuropathy caused by vasculitis syndrome.
 
Key words
Key words Churg-Strauss syndrome ・ Dextromethorphan ・ Neuropathy ・ Pain ・ Pranlukast
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