 |
MR Vol.10 No.4 indexに戻る
 |
MODERN RHEUMATOLOGY
Vol.10 No.4 |
 |
|
|
 |
|
|
An autopsy case of hepatitis B (HB) antigen-positive
polyarteritis nodosa, with reference to immunopathological studies
of vascular lesions
|
|
|
| T. Nonogaki1, S. Aoki1, K. Yoshikawa1,
T. Mitsui1 |
| (1) Division of Locomotorial Disorders, Institute
for Medical Science of Aging, Aichi Medical University, 5-1206 Akaike,
Nissin, Aichi 470-0125, Japan |
| |
| Abstract |
| Abstract An autopsy case of an 11-year-old
boy with polyarteritis nodosa is described in which the onset of
the disease was associated with the presence of hepatitis B (HB)
antigens (Ag) in the cytoplasm and nuclei of hepatocytes as detected
by immunohistological methods. Deposits of HBsAg, HBeAg, IgG, IgM,
C3, and C1q were demonstrated in systemic vascular lesions. It
is considered that the arteritis was due to deposition in the arteries
of immune complexes formed by HBAg and HB antibodies. |
| |
| Key words |
| Key words Hepatitis B antigen ・ Immune complex
・ Polyarteritis nodosa |
|
|
 |
|
|
