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MR Vol.10 No.4 indexに戻る
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MODERN RHEUMATOLOGY
Vol.10 No.4 |
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Successful treatment of reactive hemophagocytic
syndrome by plasmapheresis and high-dose %-globulin in a patient
with systemic lupus erythematosus |
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| S. Banno , Y. Sugiura1, T. Yoshinouchi1,
Y. Matsumoto1, R. Ueda1 |
(1)Second Department of Internal Medicine,
Medical School, Nagoya City University, 1 Kawasumi, Mizuho-ku,
Nagoya 460-8601, Japan
(2)Department of Clinical Laboratory Medicine, Nagoya City University, Nagoya,
Japan |
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| Abstract |
| Abstract A 31-year-old woman who had been administered
corticosteroid and immunosuppressive agents for systemic lupus erythematosus
(SLE) without flare-up was diagnosed as having reactive hemophagocytic
syndrome (HPS) with severe disseminated intravascular coagulation.
The causative underlying disease was uncertain, but it was not the
SLE itself. Her fulminant HPS with increased serum ferritin and inflammatory
cytokines (sIL-2R, TNF-!, IL-6, and IFN-%) was successfully treated
with plasmapheresis and high-dose %-globulin therapy. |
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| Key words |
| Key words Hemophagocytic syndrome ・ Virus-associated
hemophagocytic syndrome ・ Plasmapheresis ・ High-dose &ggr;-globulin
・ Systemic lupus erythematosus |
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