MR Vol.10 No.3 indexに戻る

MODERN RHEUMATOLOGY Vol.10 No.3             
Necrotizing fasciitis caused by Streptococcus pneumoniae in mixed connective tissue disease
Takamichi Yuhara1, Hiroyuki Takemura1, Takao Akama1, Kazuhide Yamane1, Takayuki Sumida1
(1)Division of Rheumatology, Department of Internal Medicine, Institute of Clinical Medicine, University of Tsukuba, 1-1-1 Tennodai, Tsukuba, Ibaraki 305-8575, Japan
 
Abstract
Abstract A 42-year-old man was hospitalized because of chills, fever, and severe polyarthralgia. He had a 5-year history of mixed connective tissue disease (MCTD) with polyarthritis which had been treated with a nonsteroidal anti-inflammatory drug alone. On the second day of hospitalization, necrotizing fasciitis of the right leg developed. Streptococcus pneumoniae was later detected in a blood culture. Pneumococcal infections of the soft tissues are uncommon, and have been reported in immunosuppressed patients and patients with systemic lupus erythematosus. This is the first report of a case of necrotizing fasciitis caused by S. pneumoniae in a patient with MCTD.
 
Key words
Key words Necrotizing fasciitis ・ Streptococcus pneu-moniae ・ Mixed connective tissue disease
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