MR Vol.10 No.2 indexに戻る

MODERN RHEUMATOLOGY Vol.10 No.2             
Dilated cardiomyopathy (DCM) associated with SSA antibody in primary Sjogren syndrome
M. Nishinarita1, M. Nakagawa1, E. Tanaka2
(1)Department of Rheumatology, Taga General Hospital, 2-1-2 Kokubu-cho, Hitachi 316-0035, Japan
(2)Institute of Rheumatology, Tokyo Women's College, Tokyo, Japan
 
Abstract
Abstract A 33-year-old Japanese woman was diagnosed with primary Sjogren syndrome (SS) in 1995. At this time, SSA antibody had not been detected by the Oucterlony or EIA methods. Two years later, the patient developed dyspnea. A chest X-ray showed cardiomegaly. An echocardiogram indicated severe diffuse hypokynesis of the cardiac wall with a left ventricular ejection fraction of 32%. Positive SSA antibody (over 500 u/ml) was noted in her serum as measured by the EIA method. We considered her cardiac manifestation to be dilated cardiomyopathy associated with primary SS.
 
Key words
Key words Dilated myopathy ・ Sjogren syndrome ・ SSA antibody ・ Cardiac manifestation ・ Elevation of IgG
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