Vol.23 No.6

Case Report

Recurrence of IgG4-related disease following treatment with rituximab

Authors

Jun Murakami 1 , Shoko Matsui2 , Shin Ishizawa3 , Kotaro Arita1 , Akinori Wada1 , Takayoshi Miyazono1 , Hiroyuki Hounoki2 , Koichiro Shinoda2 , Hirofumi Taki2 , Toshiro Sugiyama1

  • Department of Internal Medicine (3), Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
  • Department of Internal Medicine (1), Faculty of Medicine, University of Toyama, 2630 Sugitani, Toyama 930-0194, Japan
  • Department of Pathology, Toyama Prefectural Central Hospital, 2-2-78 Nishi-nagae, Toyama 930-8550, Japan
Received:

5 April 2012

Accepted:

1 August 2012

Published online:

6 September 2012

Full Text

PDF　(member's only)

Abstract

A 54-year-old woman with suspected lowgrade B-cell lymphoma of mucosa-associated lymphoid tissue type of the eyelids underwent rituximab-containing chemotherapy. She initially responded to the rituximab therapy, but later experienced two recurrences over a 3-year period. Biopsy specimens and a review of her previous histology revealed that she had had immunoglobulin G4-related disease at the initial presentation. Although IgG4-related disease seems to respond well to rituximab therapy, long-term follow up, including disease monitoring, is needed to evaluate disease remission.

Key words

IgG4-related disease, Treatment, Rituximab