Vol.23 No.3

Case Report

Takayasu arteritis developing during treatment of ulcerative colitis with infliximab

Authors

Yoshiro Horai1 , Oka Satoru1 , Samuel Lapalme-Remis2 , Remi Sumiyoshi1 , Yoshikazu Nakashima1 , Takahisa Suzuki1 , Akitomo Okada1 , Shin-ya Kawashiri1 , Kunihiro Ichinose1 , Mami Tamai1 , Satoshi Yamasaki1 , Hideki Nakamura1

  • nit of Translational Medicine, Department of Immunology and Rheumatology, Nagasaki University, Graduate School of Biomedical Sciences, 1-7-1 Sakamoto, Nagasaki 852-8501, Japan
  • Division of Neurology, Faculty of Medicine, University of Ottawa, Ottawa, ON, Canada
  • Unit of Translational Medicine, Department of Gastroenterology and Hepatology, Nagasaki University, Graduate School of Biomedical Sciences, Nagasaki, Japan
  • Unit of Translational Medicine, Department of Rehabilitation Sciences, Nagasaki University, Graduate School of Biomedical Sciences Biomedical Sciences, Nagasaki 852-8523, Japan
Received:

24 April 2012

Accepted:

24 May 2012

Published online:

21 June 2012

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Abstract

A 22-year-old female with ulcerative colitis that was successfully treated with infliximab (IFX), and remained stable following tapered discontinuation of prednisolone, developed anterior neck pain and elevation of C-reactive protein following her fourth administration of IFX. She was diagnosed with Takayasu arteritis (TA) based on neck ultrasound and computed tomography angiography. This is the first report describing the development of TA during treatment of UC with IFX.

Key words

Takayasu arteritis, Ulcerative colitis, Infliximab