Vol.23 No.1

Case Report

Mizoribine for crescentic glomerulonephritis with sarcoidosis: effectiveness not only for urinalysis abnormalities but also for hilar lymph node enlargement

Authors

Maki Kabara1 , Naoki Nakagawa1 , Motoki Matsuki1 , Junko Chinda1 , Takayuki Fujino1 , Naoyuki Hasebe1

  • Division of Cardiology, Nephrology, Pulmonology and Neurology, Department of Internal Medicine, Asahikawa Medical University, Asahikawa, Japan
Received:

31 October 2011

Accepted:

2 February 2012

Published online:

19 February 2012

Full Text

PDF　(member's only)

Abstract

Sarcoidosis is a multisystem disease related to helper T cell responses. We recently experienced the case of a 57-year-old woman with sarcoidosis complicated by crescentic glomerulonephritis with low levels of myeloperoxidase-antineutrophil cytoplasmic antibody. We herein describe the details of her clinical course and discuss the effectiveness of mizoribine, which has an immunosuppressive effect equivalent to that of mycophenolate mofetil, not only for urinalysis abnormalities but also for hilar lymph node enlargement.

Key words

Sarcoidosis - Myeloperoxidase-antineutrophil cytoplasmic antibody - Crescentic glomerulonephritis - Mizoribine