Epidural spinal tumor and periaortitis as rare complications of Wegener’s granulomatosis

Vol.21 No.6

Case Report

Epidural spinal tumor and periaortitis as rare complications of Wegener’s granulomatosis

Authors

Shimpei Kasagi¹ , Jun Saegusa¹ , Goh Tsuji¹ , Sho Sendo¹ , Natsuko Miura¹ , Hiroki Hayashi¹ , Takeshi Sugimoto¹ , Seiji Kawano¹ , Kotaro Nishida² , Kenichiro Kakutani² , Akio Morinobu¹ , Shunichi Kumagai¹

Department of Clinical Pathology and Immunology, Kobe University Graduate School of Medicine, 7-5-2 Kusunoki-Cho, Chuo-ku, Kobe, Hyogo, 650-0017, Japan
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Japan

Received:

24 January 2011

Accepted:

5 April 2011

Published online:

21 June 2011

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Abstract

This case report describes findings in a 61-yearold woman who manifested scleritis, small pulmonary nodules, otitis media, periaortitis, and progressive epidural spinal tumor, associated with elevated serum myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA) levels. She was clinically diagnosed with Wegener’s granulomatosis, although vasculitis was not diagnosed due to the lack of typical histological findings. We discuss the differential diagnosis in this patient, and the association of MPO-ANCA with periaortitis or epidural spinal tumor.

Key words

Wegener’s granulomatosis - Periaortitis - Epidural spinal tumor