Vol.21 No.5

Case Report

Lobular panniculitis with small vessel vasculitis associated with ulcerative colitis

Authors

Enrico Beccastrini1 , Giacomo Emmi1 , Danilo Squatrito1 , Gabriella Nesi2 , Fabio Almerigogna1 , Lorenzo Emmi1

  • Department of Biomedicine, Allergology and Clinical Immunology, University of Florence, Viale GB Morgagni 85, 50134, Florence, Italy
  • Division of Pathological Anatomy, Department of Critical Care Medicine and Surgery, University of Florence, Florence, Italy
Received:

1 November 2010

Accepted:

1 February 2011

Published online:

20 February 2011

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Abstract

We report a rare case of lobular panniculitis with small vessel vasculitis, presenting with fever, cutaneous lesions, and systemic manifestations involving the visceral fat and associated with ulcerative colitis. The patient was treated with cyclophosphamide and prednisolone, which successfully cured the systemic disease, with resolution of the inflammatory infiltrates.

Key words

Panniculitis - Pyoderma gangrenosum - Ulcerative colitis - Cyclophosphamide - Cyclosporine