Vol.21 No.5

Case Report

A case of juvenile idiopathic arthritis exhibiting repair of systemic bone erosion in response to continuation of MTX therapy after achievement of clinical remission

Authors

Teruyuki Nakatani1 , Toru Maekawa2 , Shinsuke Ishii1

  • Department of Orthopedic Surgery, Kishiwada City Hospital, 1001, Gakuhara-tyo, Kishiwada, Osaka, 596-8501, Japan
  • Maekawa Surgery Clinic, 3-10-19, Hachizuka, Ikeda, Osaka, 563-0024, Japan
Received:

26 July 2010

Accepted:

20 January 2011

Published online:

18 February 2011

Full Text

PDF　(member's only)

Abstract

We report a patient with rheumatoid factorpositive polyarthritis-type juvenile idiopathic arthritis (JIA) in whom clinical remission was achieved within 10 months after the start of methotrexate (MTX) therapy, and systemic repair of bone erosion was noted 8 months after clinical remission. These results indicate that even in cases of active JIA with the development of bone erosion, continuation of MTX therapy after the achievement of clinical remission can improve the prognosis, including repair of bone destruction.

Key words

Bone repair - Bone erosion - Clinical remission - Juvenile idiopathic arthritis - Methotrexate