Simultaneous presentation of hemophagocytic syndrome and mesenteric vasculitis in a patient with systemic lupus erythematosus

Vol.21 No.3

Case Report

Simultaneous presentation of hemophagocytic syndrome and mesenteric vasculitis in a patient with systemic lupus erythematosus

Authors

Su-Jin Moon¹ , Seung-Ki Kwok¹ , Kyung-Su Park¹ , Wan-Uk Kim² , Sung-Hwan Park¹ , Ho-Youn Kim¹

Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, Seoul St. Mary’s Hospital, 505 Banpo-Dong, Seocho-Gu, Seoul, 137-040, South Korea
Division of Rheumatology, Department of Internal Medicine, School of Medicine, The Catholic University of Korea, St. Vincent’s Hospital, 93 Chi-Dong, Suwon, 442-723, South Korea

Received:

12 August 2010

Accepted:

29 November 2010

Published online:

13 January 2011

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Abstract

We report an 18-year old female patient with systemic lupus erythematosus (SLE), who developed fever, pancytopenia, abdominal pain, and watery diarrhea. Computed tomography (CT) and bone marrow aspirate revealed lupus mesenteric vasculitis (LMV) and hemophagocytic syndrome (HPS). Serologic tests for Epstein-Barr virus (EBV) indicated its reactivation. This case demonstrates that HPS and concomitant LMV associated with viral reactivation can occur as clinical manifestations of SLE flare.

Key words

Epstein-Barr virus - Hemophagocytic syndrome - Lupus mesenteric vasculitis - Systemic lupus erythematosus