Vol.21 No.3

Case Report

Staphylococcal scalded skin syndrome after intra-articular injection of hyaluronic acid

Authors

Yasuo Kunugiza1 , Mamori Tani2 , Tetsuya Tomita1 , Hideki Yoshikawa1

  • Department of Orthopaedic Surgery, Osaka University, Graduate School of Medicine, Yamadaoka 2-2, Suita, Osaka, Japan
  • Department of Dermatology, Osaka University Graduate School of Medicine, Suita, Japan
Received:

22 July 2010

Accepted:

14 November 2010

Published online:

28 December 2010

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Abstract

One of the severe adverse effects of intra-articular injection in the knee is septic arthritis of the knee joint. Staphylococcus aureus is the most frequent pathogen of septic arthritis. Staphylococcal scalded skin syndrome (SSSS) refers to a spectrum of blistering skin diseases caused by S. aureus exfoliative toxins. Although SSSS is rarely observed in adults, the mortality rate is high in adult cases. We report a case of SSSS due to septic knee arthritis after intra-articular hyaluronic acid injections.

Key words

Staphylococcal scalded skin syndrome - Septic knee arthritis - Intra-articular injection