Vol.20 No.5

Case Report

Generalized laxity of connective tissue as a possible syndrome in systemic lupus erythematosus

Authors

Kyohei Nakamura1 , Yumi Tajima2 , Osamu Takai1

  • Department of Rheumatology, Osaki Citizen Hospital
  • Division of Hematology and Rheumatology, Tohoku University Graduate School of Medicine
Received:

1 April 2010

Accepted:

19 May 2010

Published online:

15 June 2010

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Abstract

We report a case of systemic lupus erythematosus (SLE) with Jaccoud’s arthropathy, presenting atlantoaxial subluxation and multiple joint hypermobility. Radiological studies showed degenerative changes, but no destructive changes like rheumatoid arthritis (RA) were observed. Since these are rare complications of SLE, the coexistence of these complications suggests that they have a common pathogenesis. Generalized laxity of connective tissues may be a novel syndrome in SLE.

Key words

Atlantoaxial subluxation - Jaccoud’s arthropathy - Joint hypermobility - Systemic lupus erythematosus