Vol.20 No.5

Case Report

A case of adalimumab-associated interstitial pneumonia with rheumatoid arthritis

Authors

Hayato Yamazaki1 , Susumu Isogai2 , Tetsushi Sakurai3 , Kenji Nagasaka1

  • Department of Rheumatology, Ome Municipal General Hospital
  • Department of Pulmonary Medicine, Ome Municipal General Hospital
  • Sakurai Clinic
Received:

26 November 2009

Accepted:

7 April 2010

Published online:

14 May 2010

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Abstract

A 64-year-old woman with rheumatoid arthritis (RA) began to complain of recurrent non-productive cough 5 months after starting adalimumab. The chest radiograph and high-resolution computed tomographic findings revealed diffuse ground-glass attenuation. Her clinical course suggested that interstitial pneumonia (IP) may have been induced by adalimumab, and she was successfully treated with a medium dose of corticosteroid. This case indicates that adalimumab-associated IP should be considered if a RA patient develops non-productive cough following adalimumab therapy.

Key words

Adalimumab - Drug-associated interstitial pneumonia - Rheumatoid arthritis