Vol.20 No.4

Case Report

An Asian case of fibroblastic rheumatism: clinical, radiological, and histological features

Authors

Shohei Watanabe1 , Kazuo Kamada1 , Hiroshi Imai1 , Haruhiko Takeda1 , Masato Nose2 , Norikazu Murata3 , Hitoshi Hasegawa4 , Haruyasu Yamamoto1

  • Department of Bone and Joint Surgery Ehime University Graduate School of Medicine Shitsukawa, Toon, Ehime 791-0295, Japan
  • Department of Pathogenomics Ehime University Graduate School of Medicine Shitsukawa, Toon, Ehime 791-0295, Japan
  • Department of Rheumatology, Yukioka Hospital 2-2-3 Ukida,Kita-ku, Osaka 530-0021, Japan
  • Department of Bioregulatory Medicine Ehime University Graduate School of Medicine,Shitsukawa, Toon, Ehime 791-0295, Japan
Received:

9 October 2009

Accepted:

8 March 2010

Published online:

15 April 2010

Full Text

PDF　(member's only)

Abstract

We report a case of fibroblastic rheumatism (FR) in a 61-year-old woman. The patient showed sclerodactyly and polyarthritis that involved both her hands and feet joints. Levels of C-reactive protein and matrix metallopeptidase-3 were within normal range. We diagnosed her condition as FR according to both the clinical features characterized with the destructive change of multiple joints and the histological sample. This is the first FR published case of FR in an Asian individual, and 23 published cases were reviewed.

Key words

Fibroblastic rheumatism - Polyarthritis - Sclerodactyly - Fibroblast