Vol.19 No.5

Case Report

Subarachnoid hemorrhage in systemic lupus erythematosus in Japan: two case reports and a review of the literature

Authors

Takayoshi Owada1 , Kentaro Takahashi1 , Yasuhiko Kita1

  • Department of Rheumatology, Yokohama Rosai Hospital, 3211 Kozukue-cho, Kohoku-ku, Yokohama Kanagawa, 222-0036, Japan
Received:

5 June 2008

Accepted:

15 June 2009

Published online:

23 July 2009

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Abstract

We report 51- and 43-year-old Japanese female patients with systemic lupus erythematosus (SLE) associated with subarachnoid hemorrhage (SAH) due to rupture of intracranial saccular aneurysms. We also review the literature of Japanese SLE patients with SAH. SAH in Japanese SLE patients is more frequent than in patients from Western countries, has different features from the general population, and can occur regardless of SLE disease activity. Clinicians must pay attention to SAH in all SLE patients.

Key words

Cerebral aneurysm - Subarachnoid hemorrhage - Systemic lupus erythematosus