Vol.19 No.5

Case Report

Lupus erythematosus tumidus in Japan: a case report and a review of the literature

Authors

Mizuho Nishiyama1 , Nobuo Kanazawa1 , Akihisa Hiroi2 , Fukumi Furukawa1

  • Department of Dermatology, Wakayama Medical University, 811-1 Kimiidera, Wakayama 641-0012, Japan
  • Hiroi Hifuhinyoukika Clinic, 5-1-1 Tanaka-machi, Wakayama 641-8329, Japan
Received:

10 March 2009

Accepted:

25 May 2009

Published online:

27 June 2009

Full Text

PDF　(member's only)

Abstract

We report here the case of a 48-year-old Japanese woman showing plaque-forming scattered indurative papules on her face, buttock and extremities. Histological examination revealed a large amount of interstitial mucin deposition, and negative direct immunofluorescence was observed. The provocative phototesting reproduced the skin lesion, and the patient was diagnosed with lupus erythematosus tumidus (LET). A review of ten LET cases previously reported in Japan revealed that all of these cases had clinicopathological features similar to those reported for European cases, although not all of the former fully satisfied the European criteria.

Key words

Direct immunofluorescence - Lupus erythematosus tumidus - Mucin deposition - Photosensitivity