Vol.19 No.2

Case Report

Nonbullous neutrophilic dermatosis: Sweet’s syndrome, neonatal lupus erythematosus, or both?

Authors

Keira L. Barr1 , Florence O’ Connell2 , Stanton Wesson2 , Vladimir Vincek3

  • Department of Dermatology, University of California Davis College of Medicine, 3301 C Street, Suite 1300, Sacramento, Davis, CA 95816, USA
  • Division of Dermatology, Department of Medicine, University of Florida College of Medicine, Gainesville, FL, USA
  • Department of Pathology and Immunology, University of Florida College of Medicine, Gainesville, FL, USA
Received:

9 May 2008

Accepted:

17 November 2008

Published online:

23 January 2009

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Abstract

We describe a 5-day-old infant who fulfilled the diagnostic criteria for Sweet’s syndrome, and the concurrent histologic and autoantibody features supporting the diagnosis of neonatal lupus. To our knowledge, this is the youngest case of Sweet’s syndrome reported in the literature. Importantly, our findings further support the hypothesis that lupus erythematosus should be considered in the differential diagnosis of a nonbullous neutrophilic dermatosis, as it may represent the initial manifestation of the disease.

Key words

Lupus erythematosus - Neonatal lupus erythematosus - Neutrophilic dermatosis - Sweet’s syndrome