Vol.18 No.3

Case Report

Osteonecrosis and monoarticular rheumatoid arthritis treated with intra-articular adalimumab

Authors

Senol Kobak1,2

  • Department of Rheumatology, Manisa Hospital, Manisa, Turkey
  • Suvari cad. 48/3 Bornova, Izmir, Turkey
Received:

13 April 2007

Accepted:

4 December 2007

Published online:

20 February 2008

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Abstract

We report a 54-year-old patient with RA presented with osteonecrosis (ON) and monoarthritis of left knee remitting in the last 2 years. Monoarthritis was resistant to disease-modifying antirheumatic drugs (DMARDs) and intra-articular corticosteroids. Intra-articular administration of adalimumab provided a good clinical and radiographic response. Synovitis resolved and osteonecrosis disappeared almost totally.

Key words

Monoarticular rheumatoid arthritis - Osteonecrosis - Adalimumab