Vol.18 No.2

Case Report

Hodgkin lymphoma as a complication of primary Sjögren’s syndrome

Authors

Isabella Lima1 , Ana Suellen B. Carneiro2 , Caroline Alencar Amorim2 , Mittermayer Barreto Santiago1,2,3

  • Rheumatology Service, Hospital Santa Izabel (HSI), Salvador, Bahia, Brazil
  • Escola Bahiana de Medicina e Saúde Pública (EBMSP), Salvador, Bahia, Brazil
  • Praça Conselheiro Almeida Couto, 500, Nazaré, Salvador, Bahia, CEP 40000-000, Brazil
Received:

17 August 2007

Accepted:

7 November 2007

Published online:

4 March 2008

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Abstract

Sjögren’s syndrome (SS) is a chronic autoimmune disease that is characterized by lymphocytic infiltration of the exocrine glands, mainly the salivary and lachrymal glands, usually manifesting with xerostomia and erophthalmia. Around 50% of patients with primary SS develop systemic complications, lymphoma being the most feared of these. The majority of these neoplasias originate from B cells and are of the non-Hodgkin type. We describe here a rare case of SS in which the patient developed a Hodgkin lymphoma. We also review the literature on this subject.

Key words

Hodgkin lymphoma - Sjögren’s syndrome