Case Report

Successful treatment of new onset Wegener’s granulomatosis with IVIG (intravenous immunoglobulin) during pregnancy: a case report

Authors

Seo Young Kim¹, Julie M. Linton¹ and Sharon L. Kolasinski¹

1. Division of Rheumatology, Department of Medicine, University of Pennsylvania, 504 Maloney, 3600 Spruce Street, Philadelphia, PA 19104, USA

Received:

23 May 2007

Accepted:

5 October 2007

Published online:

27 February 2008

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Abstract

We describe a patient with limited Wegener’s granulomatosis (WG) presenting during pregnancy with aggressive cutaneous involvement. She was treated with a combination of high-dose corticosteroids and intravenous immunoglobulin (IVIG) during her third trimester. The patient had otherwise uneventful pregnancy and a satisfactory outcome for both herself and her newborn. In the English literature, prior to this report, there have been de novo cases of WG in pregnant women that were diagnosed and treated during pregnancy and three cases of WG treated successfully with IVIG during pregnancy.

Key words

Wegener’s granulomatosis - Pregnancy - Intravenous immunoglobulin