CASE REPORT

Sarcoid myositis with muscle weakness as a presenting symptom

Authors

Hideyasu Yamada¹, Wataru Ishii¹, Satoshi Ito¹, Keiichi Iwanami¹, Hiroshi Ogishima¹, Takeshi Suzuki¹, Mizuko Mamura¹, Daisuke Goto¹, Isao Matsumoto¹, Akito Tsutsumi¹ and Takayuki Sumida¹

1. Clinical Immunology, Advanced Biomedical Applications, Graduate School of Comprehensive Human Sciences, University of Tsukuba, 1-1-1 Tennodai, Tsukuba 305-8575, Japan

Received:

19 October 2006

Accepted:

11 January 2007

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Abstract

A 54-year-old woman complaining of muscle weakness and weight loss was admitted to our hospital with suspected polymyositis. Muscle biopsy revealed Langhans-type giant cells and noncaseating granulomas. Therefore, sarcoid myositis was diagnosed. The patient was treated with prednisolone, and the symptoms improved gradually. Generally, sarcoidosis is identified clinically in patients with foggy vision or mediastinal lymphadenopathy, but muscular weakness may be an infrequently observed initial symptom. Sarcoidosis should be considered in the differential diagnosis of polymyositis.

Key words

Acute sarcoid myositis - Polymyositis - Prednisolone - Sarcoidosis