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MODERN RHEUMATOLOGY Vol.14 No.4

>MR14-4

Acute gouty arthritis during pyrazinamide treatment: a case report
Aliye Kapuk ran Tosun1, Nadide Torlak Koca1 and Gulcin Kaymak Karata1

(1) Department of Physical Medicine and Rehabilitation, Gazi University Faculty of Medicine, Senyuva Mah, Meric Sok, No. 19/C18 Bestepe, Ankara, Turkey

Received: 05 January 2004 Accepted: 23 April 2004

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Abstract

 Gout is a disease caused by an inflammatory response to an aggregation of monosodium urate crystals that develop secondary to hyperuricemia. Throughout its natural history it has four stages: asymptomatic hyperuricemia, acute gouty arthritis, intercritical gout, and chronic tophaceous gout. In this article, we report the case of a patient who had asymptomatic hyperuricemia secondary to pyrazinamide, which was prescribed for pulmonary tuberculosis, and had developed an acute gouty arthritis immediately after the "Feast of Sacrifice" due to a dietary excess of purine.
 
Key words
Diet - Gout - Hyperuricemia - Pyrazinamide - Tuberculosis
 
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