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MODERN RHEUMATOLOGY Vol.14 No.2

>MR14-2

Dermatomyositis associated with autoimmune idiopathic thrombocytopenia and anti-Ku antibody
Hiroshi Okamoto1 , Makoto Soejima1, Megumi Takeuchi1, Mutsuto Tateishi2, Chihiro Terai1, Masako Hara1, Terunobu Saito1 and Naoyuki Kamatani1
(1) Institute of Rheumatology, Tokyo Womens Medical University, 10-22 Kawada-cho, Shinjuku-ku, Tokyo, 162-0054, Japan
(2) Institute of Neurology, Tokyo Womens Medical University, Tokyo, Japan
Received: 13 August 2003 Accepted: 08 January 2004

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Abstract

 We describe a case of dermatomyositis with concurrent clinical and laboratory features of idiopathic thrombocytopenia associated with anti-Ku antibody. A diagnosis of dermatomyositis was established by the characteristic skin changes together with a muscle biopsy. Scintigraphic studies indicated cardiac involvement. Autoimmune idiopathic thrombocytopenia (AITP) has been described in association with both systemic lupus erythematosus (SLE) and scleroderma, but there are few reports describing AITP associated with myositis. To our knowledge, this is the first report of a case of dermatomyositis associated with AITP and anti-Ku antibody.
 
Key words
Anti-Ku antibody - Autoimmune idiopathic thrombocytopenia (AITP) - Dermatomyositis
 
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